In this study, we adopted two different general anesthetic techniques for Cesarean section.
Patients were randomly assigned to two groups;
Group Ⅰ ; 51 patients, thiopental-succinylcholine-nitrous oxide-oxygen supplemented with ether or halothans anesthesia.
Group Ⅱ ; 67 patients, pancuronium-thiopental-nitrous oxide-oxygen supplemented with ether or halothane anesthesia.
Group Ⅰ (Succinylcholine group):
51cases were induced for anesthesia with 150∼250㎎ of thiopental and intubated with 1㎎/㎏ of succinylcholine followed by 100% oxygen with controlled ventilation. After delivering the fetus, anesthesia was maintained with nitrous oxide-oxygen-ether or halothane throungout-the procedure.
Group Ⅱ (Pancuronium group);
Anesthesia was performed with 150∼250㎎ of thiopental, 0.08㎎/㎏ of pancuronium with endotracheal intubation for 67 patients.
After delivery, nitrous oxide with oxygen and supplemental ether or halothane were given, if necerssary.
It was concluded that incidence of hypotension was less in the pancuronium group, and no evidence of fetal effects was seen.
And there is no clinical evidence of significant placental transfer of pancuronium and that this is a safe and efficacious agent for incorporation into the nitrous oxide-relaxant anesthetic technique for Cesarean section.
No clear superiority of succinylcholine over pancuronium was demonstrated in this study.
|